Pyrilutamide (development code KX826) is a nonsteroidal antiandrogen with a high affinity silent antagonist of the androgen receptor. It is in phase II clinical trials for AGA and acne in China and the U.S.
The pyrilutamide in PyriPure is >99% pure and is formulated in an ethanol and propylene glycol solution. Each bottle comes with a calibrated pipette for easy measurements.
Efficacy
Pyrilutamide is a new compound that looks like it might be the next big thing in hair loss treatment. It’s a nonsteroidal antiandrogen that works by binding to the androgen receptor in the hair follicle. This prevents DHT from binding to it, which is responsible for baldness in men. Pyrilutamide also acts as an inhibitor of the 5-alpha reductase enzyme, which is required for testosterone to become DHT.
Kintor Pharmaceutical recently announced that they had completed enrolment for a phase III clinical trial of their first-in-class drug candidate, KX-826 (pyrilutamide) in China. The trial will assess the efficacy of the drug for treating androgenetic alopecia in male patients.
Pyrilutamide is a non-steroidal antiandrogen that has been shown to work against alopecia, as well as against acne vulgaris. It is a potent and selective high-affinity silent antagonist of the androgen receptor. It was originally developed as a prostate cancer drug, but has also been shown to be effective in the treatment of AGA and acne.
Side effects
Buy Pyrilutamide is an anti-androgen that works by blocking the binding of testosterone and DHT to the androgen receptors in hair follicles. It is a more effective treatment than minoxidil, which only slows down the thinning process. It also causes fewer side effects, including reduced libido and erectile dysfunction. It is a topical solution that can be applied to the scalp twice a day.
In a recent clinical trial, Pyrilutamide showed promising results as an alternative to finasteride and RU58841. This compound is being developed by Kintor Pharmaceuticals, a Chinese company that has self-developed multiple first-in-class compounds for treating hair loss and acne.
The drug is being developed as a topical solution and will be used in a phase II study in the US for male and female pattern baldness. Its efficacy will be evaluated by measuring the change in non-vellus target area hair count after six months of treatment. Kintor Pharma hopes that pyrilutamide will improve the lives of men and women with androgenetic alopecia.
Dosage
Pyrilutamide (development code KX-826) is a first-in-class topical AR antagonist for androgenetic alopecia. The drug is undergoing dual phase II clinical trials in both the US and China. In the US, the trial will be randomized and double-blind to observe a change in non-vellus hair over a 6-month period.
This is an extremely promising development, and it would be great if pyrilutamide were to work. It’s unclear exactly how the compound works, but it is believed to inhibit DHT and testosterone from binding to androgen receptors in the hair follicles. The drug was developed while searching for a prostate cancer treatment, but it has shown promise in treating AGA and acne as well.
PyriPure is a solution of Pyrilutamide in a propylene glycol and ethanol vehicle. It is a highly pure formulation, and every batch is tested by a 3rd party to ensure it’s >99% pure. Each bottle comes with a calibrated dropper for accurate measurements. The bottle should be stored in a dark, cool place to maintain the potency of the active compound.
Cost
Buy Pyrilutamide in Europe, or KX-826, is a non-steroidal antiandrogen that inhibits DHT and testosterone from binding to the androgen receptor in the hair follicle. It has been shown to be effective in reducing androgenic alopecia (AGA) in males. It also has a low risk of adverse effects compared to current treatments. It recently completed phase II clinical trials in China and the US.
The company that developed the drug is Kintor Pharmaceuticals Limited. It is a biotechnology company that develops innovative small molecules and biological therapeutics. Its main focus is on addressing unmet medical needs, including androgen-related diseases such as prostate cancer, alopecia, and acne vulgaris.
PyriPure is a solution of pyrilutamide in an ethanol and propylene glycol vehicle. It is third-party lab-tested for purity and comes with a calibrated dropper for precise dosage. It is stable for one year after mixing, and it should be stored in a cool environment. PyriPure is sold for research use only, and is not intended to treat any disease.
